Download PDF by Roger Narayan, Paolo Colombo, Dileep Singh, Jonathan Salem: Advances in Bioceramics and Porous Ceramics II

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By Roger Narayan, Paolo Colombo, Dileep Singh, Jonathan Salem

Increase your knowing within the most respected features of advances in bioceramics and porous ceramics. This selection of logically prepared and punctiliously chosen articles comprise the lawsuits of the “Porous Ceramics: Novel advancements and purposes” and “Next iteration Bioceramics” symposia, that have been hung on January 27-February 1, 2008.

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INTRODUCTION Bone tissue engineering is of significant importance because many serious bone injuries heal slowly and result in permanent changes in bone structure and function [I]. There are about 1 million patients with skeletal defects and injuries a year that require bone-graft reconstruction [2]. Cell-based approaches for bone grafting that utilize scaffolds fabricated from synthetic biomaterials such as metals, ceramics, polymers and composites are promising alternatives to autogenic and allogeneic bone-grafting materials [3].

The ideal pore size for a bioceramic material should approximate that of bone. It has been demonstrated that microporosity (diameter < 10 pm) allows body fluid circulation whereas macroporosity (diameter 100 pm) provides a scaffold for bone-cell colonization. It was reported that BCP ceramic with an average pore size diameter ,of 565 pm (compared to those with average pore size diameter of 300 pm) and 40% macroporosity (compared to 50% macroporosity) had greater bone ingrowth [42]. >; Biological properties: The interest of BCP concept is the equilibrium of the resorption and the bone ingrowth at the expense of the bioceramics.

Ryu et al. [31] for MgO addition into HNTCP mixtures. The decrease in the lattice parameters of p-TCP, occurs as a result of the lattice contraction due to the replacement of Ca atoms by Mg atoms with smaller radii. Except for sample IV, peak shifts with the increase in Mg content was not observed in HA peaks, which indicates that Mg incorporated preferentially into TCP phase of HAiTCP mixture [31]. 5 mole% Mg , which indicates poor crystallinity. 28 . Advances in Bioceramics and Porous Ceramics I1 Structural Investigation of Nan0 Hydroxyapatites Doped with Mgz+and F- tons CONCLUSION Density and phase transformations of HAS were studied in terms of influences of Mg2' and Fions.

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